НЕКОТОРЫЕ АСПЕКТЫ БИОХИМИИ И ФИЗИОЛОГИИ СТЕРОИДНОЙ РЕГУЛЯЦИИ У КОСТИСТЫХ РЫБ
Аннотация
Стероидные гормоны – важные регуляторы функций организма, связанных с размножением, стрессом и метаболизмом. В данном обзоре представлены сведения о путях биосинтеза стероидных гормонов у представителей класса костистых рыб в сравнении со стероидогенезом у млекопитающих (на примере человека), а также описана система стероидных рецепторов, при этом более подробно изложены сведения о рецепции кортикостероидов. Pаскрытие минералокортикоидной регуляции у рыб представлено в историческом аспекте. Приведены сведенияоб участии кортикостероидов в осморегуляции костистых рыб, механизмы которой значительно отличаются от таковых у наземных позвоночных. Несмотря на большое сходство в путях биосинтеза стероидных гормонов у рыб и млекопитающих, имеется несколько существенных различий, а именно: 1) отсутствие у костистых рыб способности к биосинтезу альдостерона, 2) возможность синтеза стероидов, индуцирующих созревание (СИС), у костистых рыб и 3) различия в путях биосинтеза андрогенов.
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Zhang Y., Zhang
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